| 发明名称 |
MODIFICATION OF BIOPOLYMERS FOR IMPROVED DRUG DELIVERY |
| 摘要 |
A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a suitable carrier, has improved <i>in vivo</i> stability and activity, and can be targeted to a variety of cells, tissues and organs.
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| 申请公布号 |
WO0160412(A2) |
申请公布日期 |
2001.08.23 |
| 申请号 |
WO2001US04925 |
申请日期 |
2001.02.15 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
CALIAS, PERICLES;MILLER, ROBERT, J. |
| 分类号 |
A61K47/48;A61P1/16;A61P7/00;A61P35/00;(IPC1-7):A61K47/48 |
主分类号 |
A61K47/48 |
| 代理机构 |
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