TRANSGENIC, NON-HUMAN ANIMALS CONTAINING A COXSACKIE/ADENOVIRUS RECEPTOR (CAR)

摘要

The invention features a transgenic animal, which expresses a Coxsackie-adenovirus receptor (CAR) in its cells. The invention provides a new animal model for effecting adenovirus-mediated gene delivery and for testing gene function in vivo, and also provides new opportunities to assess gene function in vitro using freshly isolated cells.