发明名称 PHARMACEUTICAL COMPOSITION, REAGENT AND METHOD FOR INTRACEREBRAL DELIVERY OF PHARMACEUTICALLY ACTIVE INGREDIENT OR LABELING SUBSTANCE
摘要 There are provided a pharmaceutical composition which can easily transport a pharmaceutically active ingredient into a brain, a reagent can easily transport a labeling substance into a brain, and a method for delivering a pharmaceutically active ingredient or a labeling substance from blood into a brain. The pharmaceutically active ingredient and the labeling substance are bonded to a hibernation-specific protein, and used as a conjugate. By administering the conjugate together with a thyroid hormone substance or a substance enhancing secretion and production thereof, the pharmaceutically active ingredient or the labeling substance is delivered into a brain.
申请公布号 WO0160411(A1) 申请公布日期 2001.08.23
申请号 WO2001JP01167 申请日期 2001.02.19
申请人 KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY;MITSUBISHI CHEMICAL CORPORATION;KONDO, NORIAKI 发明人 KONDO, NORIAKI
分类号 A61K38/24;A61K47/48 主分类号 A61K38/24
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