The present invention comprises piperazine-containing compounds which inhibit prenyl-protein transferases, including farnesyl-protein transferase and geranylgeranyl-protein transferase type I. Such therapeutic compounds are useful in the treatment of cancer.
申请公布号
WO0160369(A1)
申请公布日期
2001.08.23
申请号
WO2001US04868
申请日期
2001.02.15
申请人
MERCK & CO., INC.;DINSMORE, CHRISTOPHER, J.;BERGMAN, JEFFREY, M.
