发明名称 Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors
摘要 <p>The present invention provides methods of treating diabetic cardiomyopathy, the methods comprising administering to a patient having or at risk of having diabetic cardiomyopathy a therapeutically effective amount of a glycogen phosphorylase inhibitor. The present invention also provides methods of treating diabetic cardiomyopathy, the methods comprising administering to a patient having 1) diabetes and 2) having cardiovascular disease, ischemic heart disease, congestive heart failure, congestive heart failure but not having coronary arteriosclerosis, hypertension, diastolic blood pressure abnormalities, microvascular diabetic complications, abnormal left ventricular function, myocardial fibrosis, abnormal cardiac function, pulmonary congestion, small vessel disease, small vessel disease without atherosclerotic cardiovascular disease or luminal narrowing, coagulopathy, cardiac contusion, or having had or at risk of having a myocardial infarction a therapeutically effective amount of a glycogen phosphorylase inhibitor.</p>
申请公布号 EP1125580(A2) 申请公布日期 2001.08.22
申请号 EP20010300575 申请日期 2001.01.23
申请人 PFIZER PRODUCTS INC. 发明人 TREADWAY, JUDITH LEE
分类号 C07D401/12;A61K31/00;A61K31/403;A61K31/404;A61K31/4045;A61K31/407;A61K31/427;A61K31/4427;A61K31/443;A61K31/4439;A61K31/454;A61K31/496;A61K31/5355;A61K31/5377;A61K31/695;A61K38/04;A61K38/28;A61K45/00;A61K45/06;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P5/02;A61P5/14;A61P5/42;A61P5/48;A61P7/04;A61P9/00;A61P9/02;A61P9/04;A61P9/10;A61P9/12;A61P9/14;A61P11/00;A61P43/00;C07D209/42;C07D403/12;(IPC1-7):A61K31/00;A61K31/537;A61K31/535 主分类号 C07D401/12
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