发明名称 METHOD FOR PREPARING FINE POWDERY PREPARATION
摘要 PROBLEM TO BE SOLVED: To provide a method for preparing fine powdery preparation containing carotenoid especially &beta;-carotene, and having <10&mu;m, especially<1&mu;m particle diameter. SOLUTION: This method for preparing fine powdery preparation containing the carotenoid, especially the &beta;-carotene is characterized is that (a-1) the carotenoid is dissolved in dimethyl ether under a high-pressure and high-temperature condition; (a-2) the solution formed thus is flashed in an expanding device to decompress the solution; and (a-3) the fine powdery solid particles formed at the time of the expansion are separated from the discharged dimethyl ether.
申请公布号 JP2001226262(A) 申请公布日期 2001.08.21
申请号 JP20000312886 申请日期 2000.10.13
申请人 F HOFFMANN LA ROCHE AG 发明人 PETER SIEGFRIED K F;STEINER KURT;STOLLER HANSJOERG;WEIDNER ECKHARD
分类号 A61K9/14;A61K9/16;A61K31/015;A61K31/07;A61K31/192;A61K31/407;A61K31/4709;A61K31/4725;A61K31/505;A61K31/522;A61K31/5375;A61K31/542;A61K31/551;A61K31/59;A61K31/706;A61K47/32;A61K47/34;A61K47/36;A61K47/42;A61K47/44;A61P7/02;A61P9/12;A61P25/00;A61P25/16;A61P29/00;A61P31/00;A61P31/12;A61P35/00;B01J2/00;B01J3/00 主分类号 A61K9/14
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