1,3-OXATHIOLANE USEFUL FOR TREATMENT OF HEPATITIS

摘要

PROBLEM TO BE SOLVED: To provide the use of analogue of a nucleoside in the treatment of viral infection. SOLUTION: This medicinal composition for treating the infection of hepatitis B contains a pharmaceutically acceptable carrier, cis-2-hydroxymethyl-5-(5'- fluorocytosion-1'-yl)-1,3-oxathiolane or trans-2-hydroxumethyl-5-(5'-flurocytosin-1'- yl)-1,3-oxathiolane in the shape of a racemic mixture or a signal enantiomer, or a pharmaceutically acceptable salt or a mixture thereof, and at least one therapeutically active antiviral agent.