发明名称 3-DESMETHYLRAPAMYCIN OR ITS DERIVATIVE, AND USE THEREOF AS ANTIMYCOTIC AGENT AND IMMUNOSUPPRESSANT
摘要 PROBLEM TO BE SOLVED: To provide 29-desmethylrapamycin which is one of isolated compounds produced by many microorganisms as various metabolites, and was elucidated to have useful therapeutic activities, which is made clear, is considered to be a new compound, and has useful antimycotic activities and immunosuppressant characteristics. SOLUTION: The 29-desmethylrapamycin of the compound of the formula (I) or the derivative thereof is provided. The pharmaceutical composition contains the compound.
申请公布号 JP2001226380(A) 申请公布日期 2001.08.21
申请号 JP20010000167 申请日期 2001.01.04
申请人 SMITHKLINE BEECHAM PLC 发明人 SHELLEY PETER ROBIN;BANKS RHONA MARY
分类号 A61K31/445;A61K31/395;A61P31/02;A61P31/04;A61P31/10;A61P37/06;C07D498/14;C07D498/18;C12N1/20;C12P17/18;C12R1/465;(IPC1-7):C07D498/14 主分类号 A61K31/445
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