发明名称 |
Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis |
摘要 |
The invention provides compounds of the formula (I):wherein R1 is an amino or an alkyl group, optionally substituted with one or more groups selected from C1-C6 alkyl group; R2 is H or halogen; R3 is H, halogen, hydroxyl group, or alkyl group; R4 is H or halogen; and R5 is halogen, preferably chlorine; and salts and prodrugs thereof; and a method of using these compounds for the treatment of cancer.
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申请公布号 |
US6277844(B1) |
申请公布日期 |
2001.08.21 |
申请号 |
US19990395812 |
申请日期 |
1999.09.14 |
申请人 |
SPECTOR SYDNEY;SPECTOR NEIL L. |
发明人 |
SPECTOR SYDNEY;SPECTOR NEIL L. |
分类号 |
A61K31/55;A61K41/00;C07D487/04;(IPC1-7):C07D487/04;A61P35/00 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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