发明名称 Compound for selective treatment of malignant cells by inhibiting cell cycle progression, decreasing Bcl2, and increasing apoptosis
摘要 The invention provides compounds of the formula (I):wherein R1 is an amino or an alkyl group, optionally substituted with one or more groups selected from C1-C6 alkyl group; R2 is H or halogen; R3 is H, halogen, hydroxyl group, or alkyl group; R4 is H or halogen; and R5 is halogen, preferably chlorine; and salts and prodrugs thereof; and a method of using these compounds for the treatment of cancer.
申请公布号 US6277844(B1) 申请公布日期 2001.08.21
申请号 US19990395812 申请日期 1999.09.14
申请人 SPECTOR SYDNEY;SPECTOR NEIL L. 发明人 SPECTOR SYDNEY;SPECTOR NEIL L.
分类号 A61K31/55;A61K41/00;C07D487/04;(IPC1-7):C07D487/04;A61P35/00 主分类号 A61K31/55
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