发明名称 Recombinant blood-coagulation proteases
摘要 The invention relates to a non-glycosylated protein with enzymatic and serin protease activity, the zymogenous form thereof comprising the following domains of a protease of the factor IX family: (a) a catalytic domain, N-terminal bonded with (b) a zymogenous activation domain, N terminal bonded with (c) a EGF1 and/or EGF2 domain. Said protein can be used in a same way as the natural serine proteases of the factor IX family.
申请公布号 US6277618(B1) 申请公布日期 2001.08.21
申请号 US19990202101 申请日期 1999.04.12
申请人 ROCHE DIAGNOSTICS GMBH 发明人 KOPETZKI ERHARD;HOPFNER KARL-PETER
分类号 C12N15/09;C07K1/113;C07K14/48;C07K14/745;C12N9/50;C12N9/64;C12N15/00;C12R1/19;C12R1/91;(IPC1-7):C12N9/50 主分类号 C12N15/09
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