| 摘要 |
PURPOSE: Provided are phenolic compounds derived from dialkoxyethanals, their preparation process and their application. CONSTITUTION: In the phenolic compounds derived from dialkoxyethanals of formula(1), R is a dialkoxymethyl group with from 3 to 17 carbon atoms, a 1,3-dioxolan-2-yl group optionally substituted on peaks 4 and/or 5 by one or more alkyl groups comprising from 1 to 8 carbon atoms or a 1,3-dioxan-2-yl group optionally substituted on peaks 4 and/or 5 and/or 6 by one or more alkyl groups comprising from 1 to 8 carbon atoms; n has the value 1, 2 or 3 and the group or groups of formula(2) are in ortho and/or in para position of the OH group of the cycle; m represents from 0 to 4-n and X represents a functional group such as hydroxyl or halogen such as chlorine, fluorine, bromine, iodine or an alkyl or alkoxy group comprising from 1 to 8 carbon atoms or aryl group comprising from 5 to 12 carbon atoms and optionally 1 or 2 heteroatoms such as nitrogen or oxygen or carboxy or -CO- Y group in which Y represents an alkyl or alkoxy radical containing from 1 to 8 carbon or amido or amino or thiol radical, on condition that at least one of the ortho or para positions of the phenolic cycle is substituted by a hydrogen, with the exception of the compound 1 described by J. Gardent and J. Likforman, Recent Results Cancer Res. 1966, 22, 23-26 and their salts with the alkali metals, alkaline-earth metals and amines.
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