发明名称 |
DNA SEQUENCE CODING VARIABLE REGION OF ANTIBODY HAVING ENZYMATIC ACTIVITY DEGRADING GLYCOSIDIC BOND AND EXPRESSION METHOD THEREOF |
摘要 |
PURPOSE: Provided is DNA sequence that codes variable region of an antibody having enzymatic activity degrading glycosidic bond. And its expression method is also provided. CONSTITUTION: A DNA sequence coding variable region of an antibody having enzymatic activity degrading glycosidic bond is as follows: DNA sequence represented by sequence ID. No. 1 coding VH chain of antibody for glycosidase, 4f4r; DNA sequence represented by sequence ID. No. 3 coding VH chain of antibody for glycosidase, 6h4h; DNA sequence represented by sequence ID. No. 5 coding VH chain of antibody for glycosidase, Ab2l; DNA sequence represented by sequence ID. No. 7 coding antibody for glycosidase, 4f4r; DNA sequence represented by sequence ID. No. 9 coding VL chain of antibody for glycosidase, 6h4h; or DNA sequence represented by sequence ID. No. 11 coding VL chain of antibody for glycosidase, Ab2l. Wherein, all sequences are described as in the description. The antibody is prepared by expressing a fusion protein of VH and VL in an eukaryote cell or bacteria.
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申请公布号 |
KR20010076994(A) |
申请公布日期 |
2001.08.17 |
申请号 |
KR20000004484 |
申请日期 |
2000.01.29 |
申请人 |
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY |
发明人 |
CHOI, SO YEONG;JUNG, SEON JU;KWON, MI YUN;PARK, HO GUN;YOO, JAE HUN;YOON, HYEON JU |
分类号 |
C07H21/00;(IPC1-7):C07H21/00 |
主分类号 |
C07H21/00 |
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