摘要 |
Use of a compound for treating a respiratory disease in a mammal wherein the compound is a cannabinoid receptor modulator is disclosed. Compounds useful as cannabinoid receptor modulators for treating respiratory and non-respiratory leukocyte-activation associated diseases comprise compounds of formula (I), in which A and B are nitrogen or carbon, provided only one of A and B is nitrogen; and R1-R6 are as defined in the specification, wherein R2 with R5 may form a ring, and/or two R4 groups may form a six-membered aryl or heteroaryl ring, optionally having a substituent R6 forming a ring with R3.
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申请人 |
BRISTOL-MYERS SQUIBB COMPANY;LEFTHERIS, KATERINA;ZHAO, RULIN;CHEN, BANG-CHI;KIENER, PETER;WU, HONG;PANDIT, CHENNAGIRI, R.;WROBLESKI, STEPHEN;CHEN, PING;HYNES, JOHN, JR.;LONGPHRE, MALINDA;NORRIS, DEREK, J.;SPERGEL, STEVEN;TOKARSKI, JOHN |
发明人 |
LEFTHERIS, KATERINA;ZHAO, RULIN;CHEN, BANG-CHI;KIENER, PETER;WU, HONG;PANDIT, CHENNAGIRI, R.;WROBLESKI, STEPHEN;CHEN, PING;HYNES, JOHN, JR.;LONGPHRE, MALINDA;NORRIS, DEREK, J.;SPERGEL, STEVEN;TOKARSKI, JOHN |