发明名称 |
Process for the preparation of 3,5-bis(trifluoro-methyl)-benzoyl chlorides and novel 3,5-bis(tri-halogenomethyl)-and 3,5-dimethylbenzoyl halides |
摘要 |
3,5-Bis(trifluoromethyl)benzoyl chlorides optionally substituted with fluorine or chlorine are advantageously prepared by converting 3,5-dimethylbenzoic acids optionally substituted with fluorine or chlorine into the corresponding acid chlorides; completely free-radically chlorinating said chlorides in the side chains, giving 3,5-bis(trichloromethyl)benzoyl chlorides optionally substituted by fluorine or chlorine; fluorinating the latter with anhydrous hydrogen fluoride and/or antimony pentafluoride, giving 3,5-bis(trifluoromethyl)benzoyl fluorides optionally substituted with fluorine or chlorine; and then reacting the 3,5-bis(trifluoromethyl)benzoyl fluorides with silicon tetrachloride in the presence of a further Lewis acid. Some of the 3,5-bis(trihalogenomethyl) and 3,5-dimethylbenzoyl halides which arise as intermediates are novel compounds.
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申请公布号 |
US2001014759(A1) |
申请公布日期 |
2001.08.16 |
申请号 |
US20010769797 |
申请日期 |
2001.01.25 |
申请人 |
MARHOLD ALBRECHT;STOLTING JORN |
发明人 |
MARHOLD ALBRECHT;STOLTING JORN |
分类号 |
C07C51/58;C07B61/00;C07C51/60;C07C51/62;C07C63/00;C07C63/70;(IPC1-7):C07C51/58;C07C53/38;C07C55/36;C07C57/64;C07C59/00;C07C61/00;C07C62/00;C07C65/00 |
主分类号 |
C07C51/58 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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