发明名称 INDOL-3-YL DERIVATIVES
摘要 Indol-3-yl derivatives of general formula (I), wherein A, B, X, R1, R2, R3, R4, R5, n or m have the meanings given in Claim 1, and the physiologically unobjectionable salts or solvates thereof are integrin inhibitors and can be used for combating thrombosis, myocardial infarcts, coronary heart diseases, arteriosclerosis, inflammations, tumours, osteoporosis, rheumatic arthritis, macular degenerative diseases, diabetic retinopathy, infections and restenos is after angioplasty or in the event of pathological actions which are maintain ed or propagated by angiogenesis.
申请公布号 CA2399813(A1) 申请公布日期 2001.08.16
申请号 CA20012399813 申请日期 2001.01.05
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 GOODMAN, SIMON;GOTTSCHLICH, RUDOLF;WIESNER, MATTHIAS
分类号 C07D401/06;A61K31/405;A61K31/4178;A61K31/4184;A61K31/4439;A61K31/506;A61P7/02;A61P9/00;A61P9/10;A61P19/02;A61P19/10;A61P25/00;A61P27/02;A61P29/00;A61P31/00;A61P35/00;A61P43/00;C07D209/18;C07D209/20;C07D401/12;C07D401/14;C07D403/06;C07D403/12;C07D409/06;C07D417/06;C07D417/14;(IPC1-7):C07D401/12;A61K31/404 主分类号 C07D401/06
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