摘要 |
Dipeptide nitrile Cathepsin K inhibitors of formula (I), and pharmaceuticall y acceptable salts or esters thereof, in which R1 and R2 are independently H o r C1-C7 lower alkyl, or R1 and R2 together with the carbon atom to which they are attached form a C3-C8 cycloalkyl ring, and Het is an optionally substituted nitrogen-containing heterocyclic substituent, are provided, usef ul e.g. for therapeutic or prophylactic treatment of a disease or medical condition in which cathepsin K is implicated.
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