DETECTION OF BINDING OF CHARGED SPECIES USING PH- OR POTENTIAL-SENSITIVE PROBES

摘要

The extent of binding of a moiety, such as a biomolecule, to a surface, wher e the local environment at the surface has a pH or surface potential which is altered upon binding of the moiety, is determined by stably incorporating at the surface a probe which contains a pH- or potential-sensitive fluorophore.