发明名称 CONTRAST AGENTS WITH VARIABLE OXIDATION STATES
摘要 The invention relates to the use as a contrast agent in MR imaging of a physiologically tolerable lanthanide compound or salt thereof having first and second oxidation states which differ in relaxivity by a factor of at least 5, and which is convertible in vivo from said first to said second oxidation state whereby contrast is enhanced in a body region in which conversion to said second state does or does not occur.
申请公布号 EP1123116(A2) 申请公布日期 2001.08.16
申请号 EP19990950946 申请日期 1999.10.22
申请人 AMERSHAM HEALTH AS 发明人 KELLAR, KENNETH;KELLY, JAMES, DUNCAN;SCHRODER, MARTIN
分类号 A61K49/00;A61K49/06 主分类号 A61K49/00
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