| 发明名称 |
Attenuated toxins as adjuvants |
| 摘要 |
<p>Described herein are adjuvants containing as the active ingredient an attenuated toxin having a residual activity of at least 1/2000 the activity of the natural toxin and vaccines containing such adjuvants. By using, for example, attenuated natural cholera toxin, vaccines capable of showing sufficient immune potentiation in percutaneous vaccination or nasal vaccination can be presented.</p> |
| 申请公布号 |
EP1123711(A1) |
申请公布日期 |
2001.08.16 |
| 申请号 |
EP19990949324 |
申请日期 |
1999.10.20 |
| 申请人 |
THE KITASATO INSTITUTE |
发明人 |
AIZAWA, CHIKARA;SUZUKI, YUZIRO;SATO, TAKA-AKI;WATANABE, KOJI;HATTORI, NOBUAKI;TANAKA, YOSHITAKE;OMURA, SATOSHI |
| 分类号 |
A61P37/04;A61K39/39;(IPC1-7):A61K39/39;A61K39/07;A61K39/10;A61K39/21;A61K39/20;A61K39/165;A61K39/15;A61K39/118;A61K39/145;A61K39/00;A61K39/015;A61K39/02;A61K39/108;A61P31/00;A61P31/12;A61P31/04;A61K39/295;A61K39/116;A61K39/012 |
主分类号 |
A61P37/04 |
| 代理机构 |
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