| 摘要 |
The subject invention relates to compounds having the structure: (I), wherei n: (a) R1 is selected from alkyl, aryl, alkoxy, and aryloxy; (b) R3 and R4 are independently selected from hydrogen, halo, alkyl, alkoxy, alkylthio, and alkylamino, but R3 and R4 are not both hydrogen; (c) each R5 is independentl y selected from hydrogen, halo, cyano, alkyl, hydroxy, alkoxy, thio, alkylthio , amino, and alkylamino; (d) each R6 is independently selected from hydrogen, halo, nitro, cyano, alkyl, aryl, heterocyclyl, hydroxy, alkoxy, aryloxy, thi o, alkylthio, arylthio, amino, alkylamino, arylamino, acyl, alkylacyl, arylacyl , amido, alkylamido, arylamido, sulfonyl, alkylsulfonyl, arylsulfonyl, phosphonyl, alkylphosphonyl, arylphosphonyl, carboxy and its alkyl and aryl esters.The subject compounds are useful for preventing or treating reperfusi on injury of a variety of tissues.
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