发明名称 |
Processes and preparations for determining function of proteins and identification of corresponding modulators |
摘要 |
<p>The present invention provides libraries of tag dominant-negative elements (TDNE) and methods the identification specific TDNEs that act as dominant-negative elements on a target protein of interest. The present invention further relates to the use of such TDNEs and dominant-negative elements for the identification of protein-protein interactions, and the determination of a target protein's biological activity and function. Furthermore, the present invention relates to the development of means, including small molecule compounds, for disrupting the target protein's biological function and activity.</p> |
申请公布号 |
CZ20010273(A3) |
申请公布日期 |
2001.08.15 |
申请号 |
CZ20010000273 |
申请日期 |
1999.07.23 |
申请人 |
SMALL MOLECULE THERAPEUTICS, INC. |
发明人 |
MENZEL ROLF;KHAZAK VLADIMIR |
分类号 |
C12N15/09;C07K7/00;C07K14/47;C07K19/00;C12N15/10;C12Q1/02;C12Q1/68;C40B40/02;(IPC1-7):C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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