发明名称 Thiazole derivatives
摘要 <p>Compounds of formula (I)as well as pharmaceutically usable salts and esters thereof, wherein R1, R2 and R3 have the significance described in the specification, inhibit the binding of adhesive proteins to the surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. They can be used in the form of pharmaceutical preparations in the control or prevention of neoplasms, tumor metastasizing, tumor growth, osteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosis following vascular intervention, psoriasis, arthritis, fibrosis, kidney failure as well as infections caused by viruses, bacteria or fungi.</p>
申请公布号 CZ20011395(A3) 申请公布日期 2001.08.15
申请号 CZ20010001395 申请日期 1999.10.15
申请人 F. HOFFMANN-LA ROCHE AG 发明人 ALIG LEO;HILPERT KURT;WELLER THOMAS
分类号 C07D277/20;A61K31/426;A61K31/427;A61K45/00;A61K47/46;A61P1/16;A61P9/00;A61P9/10;A61P13/12;A61P17/06;A61P19/00;A61P19/02;A61P19/08;A61P19/10;A61P27/02;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P35/04;A61P43/00;C07D277/48;(IPC1-7):C07D277/58;A61P31/00;C07D277/46;C07D417/12 主分类号 C07D277/20
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