发明名称 HYPOGLYCEMIC COMPRISING ZINC (II) ORGANIC COMPLEX
摘要 PROBLEM TO BE SOLVED: To provide a hypoglycemic that has lower toxicity than vanadium, a suitable level of stability, a suitable level of lipophilicity and insulin-like action, insulin-like action and hypoglycemic action and is useful as a prophylaxis and a therapy for diabetes. SOLUTION: This hypoglycemic comprises a zinc (II) organic complex bearing pyridine ring-bearing ligand, pyrone ring-bearing ligand, thiazolidine ring-bearing ligand, amino acid ligand, or a ligand of 2-aminothiophenols, or a ligand of pyrrolidine thiocarbamate ligand (for example, trans-bis(picolinate)zinc (II) complex [Zn(PA)2(H2O)2] represented by formula 1) and a medicinal preparation that includes the zinc (II) organic complex.
申请公布号 JP2001220348(A) 申请公布日期 2001.08.14
申请号 JP20000145849 申请日期 2000.05.18
申请人 JAPAN SCIENCE & TECHNOLOGY CORP 发明人 KOJIMA YOSHITANE;SAKURAI HIROSHI
分类号 C07D333/40;A61K31/136;A61K31/145;A61K31/198;A61K31/315;A61K31/351;A61K31/381;A61K31/40;A61K31/426;A61K31/44;A61K31/4402;A61K31/4418;A61K31/455;A61K31/555;A61K33/30;A61P3/10;A61P31/10;A61P43/00;C07C229/76;C07C323/34;C07C323/52;C07D207/06;C07D213/55;C07D213/79;C07D213/80;C07D213/89;C07D277/06;C07D295/21;C07D309/38;C07D309/40;(IPC1-7):A61K31/455;A61K31/440 主分类号 C07D333/40
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