发明名称 |
METHOD OF PRODUCING EICOSAPENTAENOIC ACID OR THE ESTER DERIVATIVE THEREOF |
摘要 |
The present invention provides a continuous method of purifying eicosapentaenoic acid and esters of eicosa- pentaenoic acid, comprising (a) fractionally distilling a starting mixture containing eicosapentaenoic acid or esters of eicosapentaenoic acid using a system of at least three distillation columns connected in flow ar- rangement to separate a fraction containing eicosapentaenoic acid or esters of eicosapentaenoic acid and other C20 fatty acids from a fraction containing lower-number carbon fatty acids and from a fraction containing higher-number carbon fatty acids, and (b) continuously collecting the fraction containing eicosapentaenoic acid or esters of eicosapentaenoic acid. The pressure in the distillation columns is maintained at 10 Torr or below and the bottom temperature of the distillation columns is maintained at 210.degree.C or below.
|
申请公布号 |
CA2043615(C) |
申请公布日期 |
2001.08.14 |
申请号 |
CA19912043615 |
申请日期 |
1991.06.03 |
申请人 |
|
发明人 |
HATA, KAZUHIKO;NODA, HIDEO;MAKUTA, MASAHIRO |
分类号 |
C11B3/12;C07C51/44;C07C67/54;C11B7/00;C11C1/10;(IPC1-7):B01D3/10;C07C7/04 |
主分类号 |
C11B3/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|