发明名称 |
PROTEIN HAVING PGE2 SYNTHASE ACTIVITY AND USE THEREOF |
摘要 |
A single protein which is the principle of the PGE2 synthesis activity in a soluble fraction of the brain of rat with the administration of LPS is purified and identified. This protein has an activity of synthesizing PGE2 form PGH2 and, further, an activity of synthesizing PGE2 from arachidonic acid in consort with COX.
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申请公布号 |
WO0157225(A1) |
申请公布日期 |
2001.08.09 |
申请号 |
WO2000JP05758 |
申请日期 |
2000.08.25 |
申请人 |
CHUGAI SEIYAKU KABUSHIKI KAISHA;KUDO, ICHIRO;MURAKAMI, MAKOTO;OHISHI, SACHIKO |
发明人 |
KUDO, ICHIRO;MURAKAMI, MAKOTO;OHISHI, SACHIKO |
分类号 |
A61K38/00;C12N9/90;C12N15/61;(IPC1-7):C12N15/61;C12N5/10;A61K45/00;A61P29/00 |
主分类号 |
A61K38/00 |
代理机构 |
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