| 发明名称 |
EXTENDING THE LIFETIME OF ANTICOAGULANT OLIGODEOXYNUCLEOTIDE APTAMERS IN BLOOD |
| 摘要 |
The present invention is a complex of a polynucleotide having a property of specifically binding to a target protein together with a protein that stabilizes the polynucleotide from degradation and from clearance from the circulation <i>in vivo</i>. Methods for diagnostic imaging and therapeutic uses of the complex are disclosed.
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| 申请公布号 |
WO0078364(A3) |
申请公布日期 |
2001.08.09 |
| 申请号 |
WO2000CA00751 |
申请日期 |
2000.06.22 |
| 申请人 |
THE UNIVERSITY OF ALBERTA |
发明人 |
DOUGAN, ALFRED, H.;WEITZ, JEFFREY, I. |
| 分类号 |
C12Q1/68;A61K47/48;A61K51/00;A61P7/02;(IPC1-7):A61K51/08 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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