摘要 |
A compound of formula (I): wherein R<1>, R<2>, R<3>, R<4>, and R<5> are defined, a pharmaceutical composition comprising a therapeutically effective amount of a compound thereof above in combination with a pharmaceutically acceptable carrier, and a method of treating cerebral ischemia, epilepsy, nociception, inflammation and sepsis in a mammal in need of such treatment, comprising administering to the mammal a therapeutically effective amount of a compound thereof, a process for preparing said compounds, and compounds having the above formula wherein R<1>, R<2>, R<3>, R<4>, and R<5> are separately defined.
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