发明名称 |
C-4 CARBONATE TAXANES |
摘要 |
The present invention concerns novel taxane derivatives, their use as antitumor agents, and pharmaceutical formulations. The invention claims compounds of formula (I) and the use of compounds of formula (I) or pharmaceutical salts thereof as oral drugs for the treatment of human or veterinary disease, in which: R is phenyl, isopropyl, or tert butyl; R1 is - C(O)RZ in which RZ is (CH3)3CO-, (CH3)3CCH2-, CH3(CH2)3O-, cyclobutyl-, cyclohexyloxy, or (2-furyl); R2 is CH3C(O)O-.
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申请公布号 |
CA2399116(A1) |
申请公布日期 |
2001.08.09 |
申请号 |
CA20002399116 |
申请日期 |
2000.11.16 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ZOECKLER, MARY EDSON;KADOW, JOHN F.;HANSEL, STEVEN;TARRANT, JAMES G.;MASTALERZ, HAROLD;ROSE, WILLIAM C.;XUE, QIUFEN MAY |
分类号 |
A61K31/335;A61K31/337;A61K31/341;A61P35/00;C07D305/14;C07D407/12;(IPC1-7):C07D305/14 |
主分类号 |
A61K31/335 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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