SINGLE-USE THERAPEUTIC SUBSTANCE DELIVERY DEVICE WITH INFUSION RATE CONTROL

摘要

The single-use device has a Micro Electro Mechanical system (MEMS) flow restriction (34) with a variable infusion rate. The MEMS flow restriction is fluidly coupled to a reservoir outlet (36) to receive therapeutic substance (26) dispensed from the single-use reservoir (32) at the reservoir rate and restrict the therapeutic substance flow to a desired infusion rate. The single-use reservoir is configured for controlled collapse to dispense therapeutic substance from the reservoir at a reservoir rate through a reservoir outlet. The therapeutic substance delivery device can also be configured as a shrink polymer delivery device. A flow restriction is fluidly coupled to the shrink polymer reservoir outlet to receive therapeutic substance dispensed from the reservoir at the reservoir rate and restrict the therapeutic substance flow to an infusion rate.