| 发明名称 |
SHELL-AND-CORE DOSAGE FORM APPROACHING ZERO-ORDER DRUG RELEASE |
| 摘要 |
<p>Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by permitting diffusion of the drug from the core. The shell also promotes gastric retention of the dosage form by swelling upon imbibition of gastric fluid to a size that is retained in the stomach during the postprandial or fed mode.</p> |
| 申请公布号 |
WO0156544(A2) |
申请公布日期 |
2001.08.09 |
| 申请号 |
WO2001US03027 |
申请日期 |
2001.01.30 |
| 申请人 |
DEPOMED, INC. |
发明人 |
BERNER, BRET;LOUIE-HELM, JENNY;GUSLER, GLORIA;SHELL, JOHN, N. |
| 分类号 |
A61K9/30;A61K9/20;A61K9/28;A61K31/155;A61K31/337;A61K31/43;A61K31/472;A61K31/48;A61K31/496;A61K31/546;A61K31/704;A61K31/7048;A61K31/7052;A61K38/00;A61K47/32;A61K47/34;A61K47/36;A61K47/38;(IPC1-7):A61K9/00 |
主分类号 |
A61K9/30 |
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