| 发明名称 |
SUBSTITUTED AMINO ACIDS AS NEUTRAL SPHINGOMYELINASE INHIBITORS |
| 摘要 |
This invention relates to a series of substituted amino acids of Formula (I) , pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules that bind to neutral sphingomyelinase and inhibit its activity.
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| 申请公布号 |
CA2399792(A1) |
申请公布日期 |
2001.08.09 |
| 申请号 |
CA20012399792 |
申请日期 |
2001.02.01 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
LALAN, PRAFUL;WACHTER, MICHAEL P. |
| 分类号 |
A61K31/19;A61K31/197;A61K31/22;A61K31/405;A61K31/415;A61K31/435;A61K31/4709;A61K38/00;A61K38/55;A61P3/10;A61P9/10;A61P19/02;A61P29/00;A61P35/00;A61P43/00;C07C229/14;C07C229/22;C07D209/20;C07D215/12;C07D231/38;C07K5/06;C07K5/072;(IPC1-7):A61K31/19;C07D229/00 |
主分类号 |
A61K31/19 |
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