| 摘要 |
<p>The invention relates generally to the changes in gene expression in inflammatory diseases and renal diseases such as IgAN and NCGN. The invention relates specifically to a novel OSF-2 sequence which was identified in IgAN kidney tissue. Methods are described for diagnosing inflammatory and renal diseases, such as immunoglobulin A nephropathy by measuring the levels of OSF-2 in nucleic acid or cell samples from patients. Also described are methods of screening modulators of OSF-2.</p> |
