| 摘要 |
<p>A method for treating donor corneal tissue, e.g., allografts, so as to reduce or prevent corneal graft rejection, or for generally treating corneal inflammation so as to prevent an immune or inflammatory response of the eye is described. One aspect of the invention includes the creation of a non-allogenic epithelial layer (e.g., from living epithelial cells from the recipient or from living, commercially available non-immunogenic epithelial cells) to cover a donor corneal stroma (with associated endothelium) and the use of this composite cornea as the grafted entity. In other aspects of the invention, living epithelial cells from a patient can be used in general to prepare a protective barrier layer, e.g., a 'bandage', to quiet a corneal inflammatory response.</p> |
