| 摘要 |
The invention relates to a process for the preparation of a compound of formula (I)wherein:R<1 >represents C1-4 haloalkyl, fluorine, chlorine or bromine; and R<2 >represents hydrogen or C1-4 alkoxy; which process comprises the reaction of the corresponding ortho-nitrohalobenzene of formula (II):wherein R<1 >and R<2 >are as hereinbefore defined and X represents a fluorine or bromine atom, with, when X represents a fluorine atom:(a) an alkali metal cyanide, in a non aqueous solvent, optionally in the presence of a catalyst; orwhen X represents a bromine atom:(b) cuprous cyanide, in a non aqueous solvent, optionally in the presence of a catalyst selected from an alkali metal bromide or an alkaline earth metal bromide; or(c) an alkali metal cyanide, in a non aqueous solvent, in the presence of a catalytic amount of cuprous cyanide and a phase transfer catalyst. |
