| 发明名称 |
HIV protease inhibitors |
| 摘要 |
HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
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| 申请公布号 |
US6271235(B1) |
申请公布日期 |
2001.08.07 |
| 申请号 |
US19950478600 |
申请日期 |
1995.06.07 |
| 申请人 |
AGOURON PHARMACEUTICALS, INC. |
发明人 |
DRESSMAN BRUCE A.;FRITZ JAMES E.;KALDOR STEPHEN W.;KALISH VINCENT J.;REICH SIEGFRIED HEINZ;RODRIGUEZ MICHAEL J.;SHEPHERD TIMOTHY A.;TATLOCK JOHN H.;JUNGHEIM LOUIS NICKOLAUS |
| 分类号 |
C07D295/20;A61K31/00;A61K31/165;A61K31/33;A61K31/40;A61K31/403;A61K31/404;A61K31/435;A61K31/4353;A61K31/4365;A61K31/4427;A61K31/4433;A61K31/445;A61K31/4465;A61K31/47;A61K31/472;A61K31/4725;A61K31/4738;A61K31/4743;A61K31/495;A61K31/535;A61K31/5375;A61K31/675;A61P31/00;A61P31/12;A61P31/18;A61P43/00;C07C237/42;C07C323/42;C07C323/60;C07D207/16;C07D209/08;C07D211/60;C07D211/62;C07D213/40;C07D213/56;C07D213/81;C07D215/48;C07D215/50;C07D217/02;C07D217/06;C07D217/26;C07D233/66;C07D233/90;C07D295/205;C07D401/06;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D409/12;C07D417/12;C07D471/04;C07D495/04;C07F9/12;C07F9/62;C07K5/00;(IPC1-7):A61K31/495;C07D291/00;C07D241/36;C07D401/00 |
主分类号 |
C07D295/20 |
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