发明名称 OPTICALLY ACTIVE OXAZOLIDINEDIONE COMPOUND
摘要 PROBLEM TO BE SOLVED: To provide an optically active oxazolidinedione compound having excellent blood sugar depressing action and blood lipid depressing action and useful as an agent for the prevention and treatment of diabetes, hyperlipemia, glucose tolerance insufficiency, inflammatory diseases, arteriosclerosis, etc. SOLUTION: The present invention relates to (R)-(+)-5-[3-[4-[(5-methyl-2- phenyl-4-thiazolyl)methoxy]phenyl]propyl]-2,4-oxazolidinedione or its salt and a method for producing (R)-(+)-5-[3-[4-[(5-methyl-2-phenyl-4-thiazolyl) methoxy]phenyl]propyl]-2,4-oxazolidinedione or its salt by the cyclization reaction of (R)-2-ethoxycarbonyloxy-5-[4-[(5-methyl-2-phenyl-4-thiazolyl) methoxy]phenyl]pentanamide or its salt.
申请公布号 JP2001213880(A) 申请公布日期 2001.08.07
申请号 JP20000024773 申请日期 2000.01.28
申请人 TAKEDA CHEM IND LTD 发明人 MOMOSE YU;ODAKA HIROYUKI
分类号 C07D277/24;A61K31/425;A61K31/426;A61K31/427;A61P3/06;A61P3/10;A61P5/50;A61P9/10;A61P29/00;A61P43/00;C07D417/12;(IPC1-7):C07D417/12 主分类号 C07D277/24
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