发明名称 |
NON-HUMAN CARBONYL HYDROLASE MUTANTS, DNA SEQUENCES AND VECTORS ENCODING SAME AND HOSTS TRANSFORMED WITH SAID VECTORS |
摘要 |
Novel carbonyl hydrolase mutants derived from the amino acid sequence of naturally-occurring or recombinant non-human carbonyl hydrolases and DNA sequences encoding the same. The mutant carbonyl hydrolases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occurring or recombinant carbonyl hydrolase to encode the substitution, insertion or deletion of one or more amino acids in the amino acid sequence of a precursor carbonyl hydrolase. Such mutants have one or more properties which are different than the same property of the precursor hydrolase.
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申请公布号 |
CA1341280(C) |
申请公布日期 |
2001.08.07 |
申请号 |
CA19870536058 |
申请日期 |
1987.04.30 |
申请人 |
GENENTECH, INC. |
发明人 |
ESTELL, DAVID AARON;BOTT, RICHARD RAY;CUNNINGHAM, BRIAN C.;WELLS, JAMES ALLEN;CALDWELL, ROBERT MARK;POWER, SCOTT DOUGLAS |
分类号 |
C12N5/10;C12N9/48;C12N15/52;C12N15/57;C12N15/63;(IPC1-7):C12N9/48 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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