发明名称 |
Laulimalide compounds as microtubule stabilizing agents |
摘要 |
A method of inhibiting the proliferation of a hyperproliferative mammalian cell having a multiple drug resistant phenotype utilizing an amount of a laulimalide compound effective to disrupt the dynamic state of microtubule polymerization and depolymerization to arrest cell mitosis is disclosed, together with laulimalide compounds which find use in such method. |
申请公布号 |
AU3117301(A) |
申请公布日期 |
2001.08.07 |
申请号 |
AU20010031173 |
申请日期 |
2001.01.26 |
申请人 |
UNIVERSITY OF HAWAII;UTAH STATE UNIVERSITY |
发明人 |
SUSAN L MOOBERRY;BRADLEY S. DAVIDSON |
分类号 |
A61K31/365;A61P35/00 |
主分类号 |
A61K31/365 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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