Detection of biological target

摘要

Disclosed are core-shell type polymeric micelle compositions comprising a hydrophilic-hydrophobic block polymer carrying an antigen, an antibody or the like on the hydrophilic region wherein a compound undergoing a change in physical characteristic in response to a structural change of the micelles or a part thereof has been incorporated into the core region. These compositions can be used in an indirect agglutination reaction (or a passive agglutination reaction) for assaying an analyte (an antibody, an antigen or the like) in a biological sample.