发明名称 |
Cells and methods for the generation of transgenic pigs |
摘要 |
Disclosed are methods for the isolation of primordial germ cells, culturing these cells to produce primordial germ cell-derived cell lines, methods for transforming both the primordial germ cells and the cultured cell lines, and using these transformed cells and cell lines to generate transgenic animals. The efficiency at which transgenic animals are generated by the present invention is greatly increased, thereby allowing the use of homologous recombination in producing transgenic non-rodent animal species. |
申请公布号 |
US6271436(B1) |
申请公布日期 |
2001.08.07 |
申请号 |
US19970949155 |
申请日期 |
1997.10.10 |
申请人 |
THE TEXAS A & M UNIVERSITY SYSTEM |
发明人 |
PIEDRAHITA JORGE A.;BAZER FULLER W. |
分类号 |
A01K67/027;C12N5/074;C12N5/10;C12N15/09;C12Q1/68;(IPC1-7):C12N15/09;C12N15/00;C12N15/63;C12N5/00 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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