| 发明名称 |
Stable crystalline (6S)- and (6R)-tetrahydrofolic acid |
| 摘要 |
Pure and extremely stable crystalline (6S)- and (6R)-tetrahydrofolic acids, absolutely inert even when exposed to air and elevated temperature without stabilizers being added, are prepared by a crystallization process at a pH of >=3.5 for the preparation of crystalline (6S)-tetrahydrofolic acid and at a pH of >=2 for the preparation of crystalline (6R)-tetrahydrofolic acid.
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| 申请公布号 |
US6271374(B1) |
申请公布日期 |
2001.08.07 |
| 申请号 |
US19980013266 |
申请日期 |
1998.01.26 |
| 申请人 |
EPROVA AG |
发明人 |
MüLLER HANS RUDOLF;ULMANN MARTIN;MOSER RUDOLF;AMMANN THOMAS |
| 分类号 |
A61K31/505;A61K31/519;A61K31/525;A61P3/02;A61P7/06;A61P17/06;A61P19/02;A61P29/00;A61P33/10;A61P37/06;A61P39/02;A61P43/00;C07D239/00;C07D241/00;C07D475/04;(IPC1-7):C07D475/04 |
主分类号 |
A61K31/505 |
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