发明名称 |
Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants |
摘要 |
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective amount of a spirobicyclic ammonium moiety-containing polymer composition to a mammal, such as a human, whereby bile acids are sequestered. The polymers of the invention comprise spirobicyclic ammonium moieties and optionally, further comprise a hydrophobic substituent, a quaternary ammonium-containing substituent or a combination thereof.
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申请公布号 |
US6271264(B1) |
申请公布日期 |
2001.08.07 |
申请号 |
US19980203319 |
申请日期 |
1998.12.01 |
申请人 |
GELTEX PHARMACEUTICALS, INC. |
发明人 |
DHAL PRADEEP K.;POLOMOSCANIK STEVEN C. |
分类号 |
A61K31/787;C08F220/04;C08F220/06;(IPC1-7):A61K31/14;A61K31/045;A61K31/13;A61K31/33;A61K31/74 |
主分类号 |
A61K31/787 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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