摘要 |
The invention discloses a new polypeptide- 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase(3-beta-HSD) 57, the polynucleotide encoding said polypeptide, and a process for producing the polypeptide by recombinant DNA technology. It also discloses methods of applying the polypeptide for the treatment of various diseases, such as malignancy, hemopathy, HIV infection, immune disorders, and inflammation. This invention also discloses antagonist against said polypeptide and thereof therapy uses. In addition, it refers to the use of said polynucleotide encoding this new 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase 57.
|