发明名称 |
METHOD FOR REGULATING IL-10 WITH IL-9, AND APPLICATIONS THEREOF |
摘要 |
The invention involves the recognition of IL-9 as a molecule involved in induction of IL-10. Administration of IL-9 leads to protection against conditions where IL-10 production is warranted, such as infections by Gram negative bacteria. Examples of such conditions are septic shock and endotoxemia. Also a part of the invention are methods of treatment where IL-9 and a phosphodiesterase inhibitor are administered to a subject. Compositions, such as kits which include these two components are a part of the invention, as is treatment of conditions involving excess IL-10 production by administering an IL-9 inhibitor. |
申请公布号 |
WO0154714(A1) |
申请公布日期 |
2001.08.02 |
申请号 |
WO2001US02078 |
申请日期 |
2001.01.22 |
申请人 |
LUDWIG INSTITUTE FOR CANCER RESEARCH;UNIVERSITY OF PERUGIA |
发明人 |
GROHMAN, URSULA;VAN SNICK, JACQUES |
分类号 |
A61K38/20;A61P31/04;(IPC1-7):A61K38/20;A61K31/52 |
主分类号 |
A61K38/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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