摘要 |
The invention provides a composition for stimulating an immune response in a patient having an adenocarcinoma, including a patient having colorectal cancer, containing allogeneic tumor cells and a physiologically acceptable carrier. The allogeneic tumor cells can be SW620, COLO 205, or SW403 cells. The invention composition can also contain an allogeneic cell expressing a cytokine. An allogeneic tumor cell can additionally express CD80. The invention additionally provides a method of stimulating an immune response in a patient having an adenocarcinoma, including a patient having colorectal cancer, by administering to the patient one or more allogeneic tumor cells, wherein the allogeneic cell stimulates an immune response to autologous tumor cells in the patient.
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申请人 |
SIDNEY KIMMEL CANCER CENTER;THE IMMUNE RESPONSE CORPORATION;SOBOL, ROBERT, E.;SHAWLER, DANIEL, L.;BARTHOLOMEW, RICHARD, M.;CARLO, DENNIS, J.;GOLD, DANIEL, P. |
发明人 |
SOBOL, ROBERT, E.;SHAWLER, DANIEL, L.;BARTHOLOMEW, RICHARD, M.;CARLO, DENNIS, J.;GOLD, DANIEL, P. |