| 摘要 |
The invention relates to a group of phenylpiperazines having high affinity for the dopamine D2-receptor and are good serotonin reuptake inhibitors (SRI's). The invention relates to a group of phenylpiperazine derivatives of formula (I) wherein: a.o. x is 1) a group of formula (1) wherein: S1 is hydrogen or halogen; S2 and S3 are independently hydrogen, alkyl (1-6C), phenyl or benzyl; S4 represents two hydrogen atoms or an oxo group, S5 is H or alkyl (1-4C); and Y is C, O or S, and salts there of.
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| 申请人 |
SOLVAY PHARMACEUTICALS B.V.;VAN HES, ROELOF;VAN DER HEIJDEN, JOHANNES, A., M.;KRUSE, CORNELIS, G.;TIPKER, JACOBUS;TULP, MARTINUS, T., M.;VISSER, GERBEN, M.;VAN VLIET, BERNARD, J. |
发明人 |
VAN HES, ROELOF;VAN DER HEIJDEN, JOHANNES, A., M.;KRUSE, CORNELIS, G.;TIPKER, JACOBUS;TULP, MARTINUS, T., M.;VISSER, GERBEN, M.;VAN VLIET, BERNARD, J. |
