发明名称 NITROGEN-CONTAINING 5-MEMBERED CYCLIC COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT
摘要 Nitrogen-containing 5-membered cyclic compounds represented by the general formula (I) and nontoxic salts thereof, wherein each symbol is as defined in the description. Because of having a cysteine protease inhibitory activity, the compounds of the general formula (I) are useful as preventives and/or remedies for inflammatory diseases, diseases caused by apoptosis, diseases caused by immune response error, autoimmune diseases, diseases caused by the degradation of biological constituent proteins, shock, circulatory error, blood coagulation error, malignant tumor, acquired immunological deficiency syndrome (AIDS), AIDS related complex (ARC), parasitogenic diseases, neurodegenerative diseases, lung disorder, bone resorption diseases, hyper endocrine diseases, etc.
申请公布号 WO0155123(A1) 申请公布日期 2001.08.02
申请号 WO2001JP00474 申请日期 2001.01.25
申请人 ONO PHARMACEUTICAL CO., LTD.;OHMOTO, KAZUYUKI;ITAGAKI, IORI 发明人 OHMOTO, KAZUYUKI;ITAGAKI, IORI
分类号 A61K31/41;A61K31/4245;A61K31/4439;A61K31/454;A61K31/5377;C07D257/04;C07D257/06;C07D271/06;C07D271/07;C07D401/04;C07D401/06;C07D403/12;C07D413/04;C07D413/06;(IPC1-7):C07D259/04;C07D271/10;C07D401/14;C07D401/12;C07D413/14;C07D413/12;C07D409/12;C07D405/12;C07D405/14;A61K31/424;A61K31/443;A61K31/537 主分类号 A61K31/41
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