发明名称 |
TRANSGENIC PLANT-BASED VACCINES |
摘要 |
A DNA construct that encodes, upon expression in plant cell, a fusion protein comprising a multimeric cholera toxin B subunit and a first immunogenic antigen from a causal factor of a mammalian disease. A DNA construct that encodes, upon expression in a plant cell, a fusion protein comprising a cholera toxin A2 subunit, a multimeric cholera toxin B subunit, a fist immunogenic antigen from a causal factor of a mammalian disease, and a first immunogenic antigen from a causal factor of a mammalian disease. A method of inducing partial or complete immunity to an infectious disease in a mammal comprising providing to the mammal for oral consumption an effective amount of the plant transformed with a construct according to the present invention.
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申请公布号 |
WO0155169(A1) |
申请公布日期 |
2001.08.02 |
申请号 |
WO2001US02663 |
申请日期 |
2001.01.29 |
申请人 |
LOMA LINDA UNIVERSITY;LANGRIDGE, WILLIAM, H., R.;YU, JIE;ARAKAWA, TAKESHI |
发明人 |
LANGRIDGE, WILLIAM, H., R.;YU, JIE;ARAKAWA, TAKESHI |
分类号 |
A61K39/00;C07K14/28;C12N15/82;(IPC1-7):C07H21/04 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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