发明名称 |
VZV ORF29P PROTEIN-RELATED COMPOSITIONS AND METHODS |
摘要 |
The present invention provides compositions of matter comprising 29p protein having bound thereto an agent whose delivery into a eukaryotic cell is desired. The present invention also provides a monoclonal antibody which specifically binds to 29p protein. The present invention further provides methods for delivering an agent into a eukaryotic cell, and methods for causing a eukaryotic cell to secrete a desired protein in the form of a fusion protein. The present invention further provides 29p protein-containing pharmaceutical compositions. The present invention still further provides nucleic acid molecules which hybridize to at least a portion of a nucleic acid molecule encoding 29p protein. Finally, the present invention provides methods for detecting the presence of, and quantitatively determining the amount of, a 29p protein-encoding nucleic acid molecule in a sample.
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申请公布号 |
WO0154709(A1) |
申请公布日期 |
2001.08.02 |
申请号 |
WO2001US02500 |
申请日期 |
2001.01.25 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
SILVERSTEIN, SAUL;ANNUNZIATO, PAULA;GERSHON, ANNE;LUNGU, OCTAVIAN |
分类号 |
A61K9/127;A61K38/00;A61K47/48;A61K48/00;C07K14/145;(IPC1-7):A61K38/00;A61K39/395;C12N15/00;C12N15/63;C12N15/88;C07H21/04 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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