发明名称 |
Intracellular amyloid-beta peptide binding (ERAB) polypeptide |
摘要 |
The present invention provides an isolated nucleic acid encoding an endoplasmic reticulum associated amyloid-beta peptide binding (ERAB) polypeptide. The ERAB polypeptide may comprise human ERAB polypeptide. The present invention provides a purified ERAB polypeptide, as well as a method for treating a neurodegenerative condition in a subject which comprises administering to the subject an agent in amount effective to inhibit ERAB polypeptide binding to amyloid-beta peptide so as to thereby treat the neurodegenerative condition.
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申请公布号 |
US6268479(B1) |
申请公布日期 |
2001.07.31 |
申请号 |
US19970815225 |
申请日期 |
1997.03.12 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK |
发明人 |
STERN DAVID M.;YAN SHI DU |
分类号 |
A61K38/00;C07K16/40;C12N9/04;C12N15/12;G01N33/68;(IPC1-7):C07K14/435 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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